Patients who carry Staph aureus in their nares or on their skin are more likely to develop Staph aureus SSIs. This is true for methicillin-resistant as well as methicillin-sensitive Staph aureus.
Kluytmans JA, Mouton JW, Ijzerman EP, Vandenbroucke-Grauls CM, Maat AW, Wagenvoort JH, et al. Nasal carriage of Staphylococcusaureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis. 1995;171:216-9.
Huang SS, Platt R. Risk of methicillin Staphylococcusaureus infection after previous infection or colonization. Clinical Infectious Diseases. 2003;36(3):281-5.
Rao N, Cannella BA, Crossett LS, Yates AJ, McGough RL, Hamilton CW. Preoperative Screening/Decolonization for Staphylococcus aureus to Prevent Orthopedic Surgical Site Infection. J Arthroplasty 2011.
Pre-op Screening for MRSA and Staph aureus: Patients are sources for Staph aureus
SSI rate 2-9x higher in carriers
Kluytmans J, van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997 Jul;10(3):505-20. doi: 10.1128/CMR.10.3.505. PMID: 9227864; PMCID: PMC172932.
Perl TM, Golub JE. New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother. 1998 Jan;32(1):S7-16. doi: 10.1177/106002809803200104. PMID: 9475834.
Wenzel RP, Perl TM. The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection. J Hosp Infect. 1995 Sep;31(1):13-24. doi: 10.1016/0195-6701(95)90079-9. PMID: 7499817.
Kalmeijer et al, Nasal carriage only independent risk factor for S. aureus SSI in orthopaedic implant surgery. Infect Control Hosp Epidemiol 2000.
Kluytmans J, van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997 Jul;10(3):505-20. doi: 10.1128/CMR.10.3.505. PMID: 9227864; PMCID: PMC172932.
Perl TM, Golub JE. New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother. 1998 Jan;32(1):S7-16. doi: 10.1177/106002809803200104. PMID: 9475834.
Wenzel RP, Perl TM. The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection. J Hosp Infect. 1995 Sep;31(1):13-24. doi: 10.1016/0195-6701(95)90079-9. PMID: 7499817.
Kalmeijer et al, Nasal carriage only independent risk factor for S. aureus SSI in orthopaedic implant surgery. Infect Control Hosp Epidemiol 2000.
| Edmiston C, Spencer M_et_al_-_Is_Staphylococcal_Screening_and_Suppression_for_SSI_Reduction___Surg_Infec_Vol_17_No_2016.pdf |
| Humphreys H, Spencer M et al. MRSA and SSI: Benefits of Screening and Decolonization before Surgery. Journal of Hospital Infection 2016.pdf |
| Edmiston C, Leaper D. Yin_and_Yang_Pre-op_Screenining for MRSA Wound Medicine, July 2013, |
| Spencer M. et al. Use_of_On-Demand_PCR_for_MRSA, C Diff, MTB. APIC 2016df |
| Kim D, Spencer, M et al Prescreening Before Othopedic Surgery for MRSA and MSSA. JBJS 2010.pdf |
MRSA Patients Contaminate the Hospital Environment When Undiagnosed
MRSA-infected/colonized patients contaminate rooms,
contribute to endemic MRSA
A prospective study of 25 MRSA patients - samples obtained
in their isolation rooms
Results:
–53.6% of surface samples were positive
–28% of air samples
–40.6% of settle plates - Isolates identical/closely related in 70% of pts
Sexton, T., Clark, P., O’Neill, E., Dillane, T. and Humphreys, H. (2006) Environmental Reservoirs of Methicillin-Resistant Staphylococcus aureus in Isolation Rooms: Correlation with Patient Isolates and Implications for Hospital Hygiene. Journal of
Hospital Infection, 62, 187-194. http://dx.doi.org/10.1016/j.jhin.2005.07.017
contribute to endemic MRSA
A prospective study of 25 MRSA patients - samples obtained
in their isolation rooms
Results:
–53.6% of surface samples were positive
–28% of air samples
–40.6% of settle plates - Isolates identical/closely related in 70% of pts
Sexton, T., Clark, P., O’Neill, E., Dillane, T. and Humphreys, H. (2006) Environmental Reservoirs of Methicillin-Resistant Staphylococcus aureus in Isolation Rooms: Correlation with Patient Isolates and Implications for Hospital Hygiene. Journal of
Hospital Infection, 62, 187-194. http://dx.doi.org/10.1016/j.jhin.2005.07.017
NOZIN ALCOHOL BASED NASAL ANTISEPTIC www.nozin.com
Perioperative care:
• Reduce Staphylococcus aureus nasal carriage in the patient prior to surgery
• Reduce Staphylococcus aureus nasal carriage of everyone who comes in contact with the patient before, during and after surgery
• Maintain decolonization of the patient and caregivers during post-operative period to help reduce complications that often lead to readmission.
• Reduce Staphylococcus aureus nasal carriage in the patient prior to surgery
• Reduce Staphylococcus aureus nasal carriage of everyone who comes in contact with the patient before, during and after surgery
• Maintain decolonization of the patient and caregivers during post-operative period to help reduce complications that often lead to readmission.
| Nozin-Clinical-Studies.pdf |
| Nozin_Surgery_360_program_bifold_060315.pdf |
| nozin_in_vitro_chart-2.pdf |
| Reduction_of_Nasal_Staph_aureus_Carriage_in_Health_care_Professionals.pdf |
3M and Sage: Skin and Nasal Antiseptic Decolonization Before Surgery
3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation. This is the first product designed to reduce S. aureus in the nasal passages or nares and is applied in the healthcare setting prior to surgery. Clinical studies show that the antiseptic kills 99.5% of S. aureus in the nares in one hour and maintains that level for at least twelve hours, an important benefit for patients undergoing surgery who may be at risk for infection.1
“Staphylococcus aureus is the leading cause of surgical site infections with approximately 80 percent of S. aureus infections caused by the patient’s own nasal flora2,” said Matt Scholz, corporate scientist, Infection Prevention Division at 3M. “As a patient preoperative skin preparation, 3M Skin and Nasal Antiseptic helps reduce the risk of S. aureus surgical site infection, including MRSA, which provides healthcare providers with confidence and control.”
“Staphylococcus aureus is the leading cause of surgical site infections with approximately 80 percent of S. aureus infections caused by the patient’s own nasal flora2,” said Matt Scholz, corporate scientist, Infection Prevention Division at 3M. “As a patient preoperative skin preparation, 3M Skin and Nasal Antiseptic helps reduce the risk of S. aureus surgical site infection, including MRSA, which provides healthcare providers with confidence and control.”
| phillips_et_al_iche_july_2014.pdf |
| 3m™_skin_and_nasal_core_brochure.pdf |
| jama_surgery_mar_2015_decolonzation_with_iodophor_antiseptic_and_chg_wash_preop_op.pdf |
| dec_2016_ic_today_nasal_decolonization.pdf |
| IDweek-pre_and_post_operative orthopedic patients and surgical staff in novel intervention to reduce S aureus abstract_10-27-16.pdf |
