7 S Bundle|SSI|Surgical Site Infection|Surgery|Surgical Infection Prevention|HAIs|Working Toward Zero
  • 7 S Bundle Steps
  • #1 Safe Operating Room
  • # 2 Screening and Decolonization
  • #3 Showers before surgery with Chlorhexidine
  • #4 Surgical Skin Prep
  • #5 Solution - Antiseptic Irrigation
  • #6 Sutures - Antimicrobial Sutures
  • #7 Seal Incision - Topical Incisional Adhesive or Antimicrobial Dressings
  • About Us and Contact Form
Edmiston C, Spencer M_et_al_-_Is_Staphylococcal_Screening_and_Suppression_for_SSI_Reduction___Surg_Infec_Vol_17_No_2016.pdf
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Humphreys H, Spencer M et al. MRSA and SSI: Benefits of Screening and Decolonization before Surgery. Journal of Hospital Infection 2016.pdf
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Patients who carry Staph aureus in their nares or on their skin are more likely to develop Staph aureus SSIs. This is true for methicillin-resistant as well as methicillin-sensitive Staph aureus.
 
​Kluytmans JA, Mouton JW, Ijzerman EP, Vandenbroucke-Grauls CM, Maat AW, Wagenvoort JH, et al. Nasal  carriage of Staphylococcusaureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis. 1995;171:216-9.

Huang SS, Platt R. Risk of methicillin Staphylococcusaureus infection after previous infection or colonization. Clinical Infectious Diseases. 2003;36(3):281-5.


 Rao N, Cannella BA, Crossett LS, Yates AJ, McGough RL, Hamilton CW. Preoperative Screening/Decolonization for Staphylococcus aureus to Prevent Orthopedic Surgical Site Infection. J Arthroplasty 2011.


Pre-op Screening for MRSA and Staph aureus: Patients are sources for Staph aureus

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Kalmeijer et al,
Nasal carriage only independent risk factor for S. aureus SSI in orthopaedic implant surgery. Infect Control Hosp Epidemiol 2000.

SSI rate 2-9x higher in carriers
–Kluytmans et al, Clin Microbiol Rev 1997
–Perl et al, Ann Pharmacother 1998
 –Wenzel et al, J Hosp Infect 1995 

 S.aureus isolates from wound match nares 85% of time
 –Perl et al, N Engl J Med 2002
–Evidence: important to screen for BOTH Staph aureus and MRSA

journ_hosp_infec_ssi__screening_2016.pdf
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mrsa_screening_orthopedics_jama_article_2015.pdf
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edmiston_c_-_yin_and_yang_pre-op_screening_for_mrsa_apr_2013.pdf
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collateral_benefit_of_screening_for_mrsa_-_ajic_jan_2015.pdf
File Size: 413 kb
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farley_jcm_2008__pcr_vs_chromagar__dec_2007.pdf
File Size: 130 kb
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chen_clin_orthop_relat_2013_pre__op_screen_is_cost_effective.pdf
File Size: 420 kb
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preoperative_decolonization_effective_at_reducing_staphylococcal_colonization_in_total_joint_arthroplasty_patients_2013.pdf
File Size: 489 kb
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blanc_jcm_2011_pcr_and_meca_gene.pdf
File Size: 118 kb
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preoperative_decolonization_effective_at_reducing_staphylococcal_colonization_in_total_joint_arthroplasty_patients_2013.pdf
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shepardjamasurg2013__cost_of_ssis.pdf
File Size: 380 kb
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everhart_-_risk_factors_for_orthopedic_surgery_corr_2013_ssi.pdf
File Size: 292 kb
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preoperative_decolonization_effective_at_reducing_staphylococcal_colonization_in_total_joint_arthroplasty_patients_2013.pdf
File Size: 489 kb
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staph_aureus_decolonization_for_ssi_prevention_metanalysis_schweizer_bmj_2013.pdf
File Size: 1364 kb
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mass_hospital_leaders_statement_on_sa_preop_screening_final_1-31-13.doc
File Size: 34 kb
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preventing_surgical_site_infections_in_nasal_carriaers_2010.pdf
File Size: 392 kb
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mrsa_clinical_practice_guidelines_idsa_liu_cid_2010.pdf
File Size: 348 kb
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infect_control_hosp_epidemiol_2000_nasal_carriage....pdf
File Size: 75 kb
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nejm_2002_intranasal_mupirocin_to_prevent....pdf
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GeneXpert from Cepheid - Polymerase Chain Reaction - Rapid Testing Technology

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The tremendous increase of both hospital acquired and community acquired MRSA in skin and soft tissue infections requires a change in management of these infections. Cepheid's on-demand Xpert MRSA/SA SSTI test detects the presence of S. aureus (SA) or methicillin-resistant S. aureus (MRSA) in skin and soft tissue infections in less than one hour.

The only rapid and comprehensive SSTI test available
  • Xpert MRSA/SA SSTI is a rapid, on-demand test for detecting MRSA and SA from skin and soft tissue swabs in less than one hour
  • Xpert MRSA/SA SSTI is the most comprehensive Staph aureus test available:
    • Includes targets for Staph aureus, MRSA, and mecA​​
    • Identifies presumptive positive "empty cassette" strains for correct classification as SA sensitive
    • Unparalleled automation with the GeneXpert® System provides reduced hands-on time and improved laboratory efficiency

apic_june_12_2016__use_of_on-demand_pcr_for_mrs_c_diff_mtb.pdf
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mgh_study_on_mrsa_and_pcr_testing_-_clin_infec_dis_april_2013.pdf
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catanzaro_cirone_real-time_polymerase_chain_reaction_testing_cdiff_ajic____1_copy.pdf
File Size: 191 kb
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nyman_cost_screening_icu_patients_mrsa_2011.pdf
File Size: 145 kb
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group_b_strep_and_pcr_in_nejm.pdf
File Size: 258 kb
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costs_and_effects_of_selective_mrsa_screening.pdf
File Size: 487 kb
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3_-_cost_comparison_of_mrsa_screening_and_management_a_decision_tree_analysis.pdf
File Size: 380 kb
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rapid_screening_for_mrsa_in_abscesses_in_emergency_dept_nov_2013.pdf
File Size: 244 kb
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cdc_-_mmwr_xpert_october_2013.pdf
File Size: 281 kb
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mrsa_and_mssa_-_jbjs_2010.pdf
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cepheid_ondemand_newsletter_9-08.pdf
File Size: 1195 kb
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costs_and_effects_of_selective_mrsa_screening.pdf
File Size: 487 kb
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schweizer_bmj_2013_bundles_in_ortho_surg_-_meta_analysis.pdf
File Size: 1364 kb
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peterson_clin_micro_infect_2013_mecc_prevalence_denmark.pdf
File Size: 591 kb
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farley_jcm_2008__pcr_vs_chromagar__dec_2007.pdf
File Size: 130 kb
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diekema_iche_2011_current__practices_in_s_aureus_screening_and_decolonization.pdf
File Size: 234 kb
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chen_clin_orthop_relat_2013_pre__op_screen_is_cost_effective.pdf
File Size: 420 kb
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blanc_jcm_2011_pcr_and_meca_gene.pdf
File Size: 118 kb
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gene-ohm_staphsr.pdf
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geneohm-assays-reimbursement.pdf
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MRSA Patients Contaminate the Hospital Environment When Undiagnosed

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•MRSA infected/colonized patients contaminate rooms, contribute to endemic MRSA
•A prospective study of 25 MRSA patients - samples obtained in their isolation rooms 
​Results:                                
–53.6% of surface samples positive                                
–28% of air samples                               
–40.6% of settle plates                              
--Isolates identical or closely related in 70% of patients
Ref:  Sexton et al, J Hosp Infect 2006

NOZIN ALCOHOL BASED NASAL APPLICATOR  www.nozin.com
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• Perioperative care: Reduce nasal carriage in the patient and everyone around the patient before, during and after surgery
• Reduce Staphylococcus aureus nasal carriage in the patient prior to surgery
• Reduce Staphylococcus aureus nasal carriage of everyone who comes in contact with the patient before, during and after surgery
• Maintain decolonization of the patient and caregivers during post-operative period to help reduce complications that often lead to readmission



nozin_surgery_360_program_bifold_060315.pdf
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nozin_in_vitro_chart-2.pdf
File Size: 322 kb
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reduction_of_nasal_staph_aureus_carriage_in_health_care__professionalsd.pdf
File Size: 436 kb
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3M and Sage: Skin and Nasal Antiseptic Decolonization Before Surgery

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3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation.
http://www.3m.com/3M/en_US/company-us/all-3m-products/~/All-3M-Products/Surgical-Solutions/Nasal-Antiseptic/Health-Care/Medical/?N=5002385+8707795+8707798+8710847+8711017+8711100+3294857497&rt=r3


3M™ Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w (0.5% available iodine) USP) Patient Preoperative Skin Preparation. This is the first product designed to reduce S. aureus in the nasal passages or nares, and is applied in the healthcare setting prior to surgery. Clinical studies show that the antiseptic kills 99.5% of S. aureus in the nares in one hour and maintains that level for at least twelve hours, an important benefit for patients undergoing surgery who may be at risk for infection.1

“Staphylococcus aureus is the leading cause of surgical site infections with approximately 80 percent of S. aureus infections caused by the patient’s own nasal flora2,” said Matt Scholz, corporate scientist, Infection Prevention Division at 3M. “As a patient preoperative skin preparation, 3M Skin and Nasal Antiseptic helps reduce the risk of S. aureus surgical site infection, including MRSA, which provides healthcare providers with confidence and control.”

phillips_et_al_iche_july_2014.pdf
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3m™_skin_and_nasal_core_brochure.pdf
File Size: 958 kb
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jama_surgery_mar_2015_decolonzation_with_iodophor_antiseptic_and_chg_wash_preop_op.pdf
File Size: 156 kb
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dec_2016_ic_today_nasal_decolonization.pdf
File Size: 624 kb
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IDweek-pre_and_post_operative orthopedic patients and surgical staff in novel intervention to reduce S aureus abstract_10-27-16.pdf
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