Surgical Antiseptic Irrigation
Irrigation of the surgical field is commonly performed prior to wound closure to reduce contamination and support optimal healing. The use of antimicrobial agents for irrigation at the site of potential contamination is intuitively appealing. However, the addition of antibiotics or other substances to irrigation solutions remains controversial. For such additives to exert a meaningful antimicrobial effect, prolonged exposure times would likely be required durations that are not typically achieved during intraoperative irrigation.
Despite this limitation, a variety of additives have been described in the literature, including antibiotics, antiseptics, and surfactants. Antibiotics reported for irrigation use, either alone or in combination, include neomycin, polymyxin, cefazolin, kanamycin, gentamicin, and vancomycin. Antiseptic agents with broad-spectrum activity against bacteria, viruses, and fungi have include iodophors and chlorhexidine gluconate. Historically, surfactants were utilized prior to the widespread adoption of antimicrobial agents; commonly used examples include benzalkonium chloride and castile soap.
Irrigation of the surgical field is commonly performed prior to wound closure to reduce contamination and support optimal healing. The use of antimicrobial agents for irrigation at the site of potential contamination is intuitively appealing. However, the addition of antibiotics or other substances to irrigation solutions remains controversial. For such additives to exert a meaningful antimicrobial effect, prolonged exposure times would likely be required durations that are not typically achieved during intraoperative irrigation.
Despite this limitation, a variety of additives have been described in the literature, including antibiotics, antiseptics, and surfactants. Antibiotics reported for irrigation use, either alone or in combination, include neomycin, polymyxin, cefazolin, kanamycin, gentamicin, and vancomycin. Antiseptic agents with broad-spectrum activity against bacteria, viruses, and fungi have include iodophors and chlorhexidine gluconate. Historically, surfactants were utilized prior to the widespread adoption of antimicrobial agents; commonly used examples include benzalkonium chloride and castile soap.
| Edmiston C, Spencer M, et al Considering a New Domain For Antimicrobial Stewardship - Topical Antibiotics AJIC 2017pdf |
| Edmiston C, Leaper D. Intra-Operative Surgical Irrigation of the Surgical Incision: What Does the Future Hold? Surg Infect 2016.pdf |
| Fry D Topical Antimicrobials and the Open Surgical Wound Surgical Infections 2016.pdf |
| Irrisept Presentation_.pdf |
0.05% CHG Surgical Irrigation - http://www.irrisept.com/
IrriSept and IrriSept O.R. are the only FDA-Cleared Cleansing and Debridement products with Chlorhexidine Gluconate (CHG) contained in the solution. The 0.05% concentration of CHG in IrriSept has been shown effective in laboratory testing against a variety of bacteria and fungi, including MRSA and Pseudomonas. The IrriSept solution is delivered through manual bottle compression in less than 30 seconds with adequate pressure to effectively remove wound debris and bacteria without harming underlying tissues. A unique set of Irrigation Applicators facilitate splatter protection and decrease aerosolized contamination during use, helping protect the patient and healthcare professionals.
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| mueller_t_et_al_intraoperative_wound_irrigation_to_prevent_colon_ssi_-_iche_2017.pdf |
| does_wound_irrigation_with_clorhexidine_reduce_ssi_in_closure_of_temp_loop_ileostomy_surg_infections_july_2018.pdf |
| Irrisept_-_In_Vivo_Studies.pdf |
| Irrisept_FAQs.pdf |
| Surgical_Irrigation_-AJIC_May_2014.pdf |
| Edmiston_et_al_AJIC_May_2013_CHG_paper.pdf |
| Edmiston_-_Irrisept_-_Log_Reduction_Study_2012_05_08_3.pdf |
| Irrisept_OR_Economics_2012.pdf |
| OBGYN-_Committee_Opinion_571_Surg_Prep_of_Vagina.pdf |
| CHG_-_Ocala_Regional_Medical_Center.pdf |
| Bingham_j_Presentation_Abstract_AAOS_2014_copy.pdf |
| mueller_t_et_al_intraoperative_wound_irrigation_to_prevent_colon_ssi_-_iche_2017.pdf |
BD Surgiphor™ Antimicrobial Irrigation System | BD
BD Surgiphor™ Antimicrobial Irrigation System is the only pre-mixed, terminally sterile dilute povidone-iodine (PVP-I) wound irrigation system. It is ready to use, enabling you to directly deliver a dilute PVP-I lavage to mechanically loosen and remove debris and foreign materials, including microorganisms from wounds during surgery. Using the BD Surgiphor™ System, you can reduce variability in wound irrigation processes, standardize wound irrigation practice and formulation for your patients, and align with current guidelines from the CDC1, WHO2, and the American Academy of Orthopaedic Surgeons (AAOS)3 to use dilute PVP-I for surgical wound irrigation.
BD Surgiphor™ Antimicrobial Irrigation System
BD Surgiphor™ Antimicrobial Irrigation System
Bactisure® Wound Lavage | Zimmer Biomet
- Bactisure Wound Lavage facilitates easy removal of microorganisms via pulsed lavage.
Exposed bacteria are subject to lavage removal or inactivation via traditional antibiotics and the body’s normal defense mechanisms. Active ingredients includes benzalkonium chloride (surfactant), and water. Product is available in sterile 1000 mL polypropylene plastic bags with an integrated single spike port. - Bactisure® Wound Lavage | Zimmer Biomet
BIASURGE™ Advanced Surgical Solution - Sanara MedTech
- A No-Rinse Surgical Solution With Staying Power BIASURGE™ ADVANCED SURGICAL SOLUTION is a no-rinse irrigation solution. It contains an antimicrobial preservative effective against a broad spectrum of pathogenic microorganisms. It is indicated for use in the mechanical cleansing and removal of debris, including microorganisms, from surgical wounds.
The ingredients in BIASURGE™ Advanced Surgical Solution work synergistically to disrupt the biofilm's extracellular polymeric substances (EPS), which protect bacteria from antibiotics and biocides. - BIASURGE® Advanced Surgical Solution | Sanara MedTech | No Rinse Irrigation Solution | Mechanical Cleansing and Removal of Debris
Ingredients:
- PHMB (polyhexamethylene biguanide)
Vicinal Diols
EDTAs (ethylenediamine tetra-acetic acid)
Poloxamer 407 (a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers)
*synergistic ingredients: Eliminates 99.9999% of bacteria within 60 seconds
Prevents biofilm formation on various tissues and implant materials for at least 24 hours
No secondary rinse necessary
Compatible with various surgical implants and closure methods
